Recombinant Human HIST1H2BK, GST-tagged

• Cat.No.: HIST1H2BK-13795H
• Product Overview: Recombinant Human HIST1H2BK protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-126a.a.
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family. This gene is found in the histone microcluster on chromosome 6p21.33.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HIST1H2BK histone cluster 1, H2bk [ Homo sapiens ]
• Official Symbol: HIST1H2BK
• Synonyms: HIST1H2BK; histone cluster 1, H2bk; H2B histone family, member T , H2BFT, histone 1, H2bk; histone H2B type 1-K; H2BFAiii; H2B K; histone 1, H2bk; histone family member; HIRA-interacting protein 1; H2B histone family, member T; H2B/S; H2BFT; MGC131989
• Gene ID: 85236
• mRNA Refseq: NM_080593
• Protein Refseq: NP_542160
• UniProt ID: O60814
• Chromosome Location: 6p22.1
• Pathway: Amyloids, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem; Gene Expression, organism-specific biosystem; Meiosis, organism-specific biosystem
• Function: DNA binding