Recombinant Human HIST1H2AC, GST-tagged

Cat.No. : HIST1H2AC-13794H
Product Overview : Recombinant Human HIST1H2AC protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-130a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name HIST1H2AC histone cluster 1, H2ac [ Homo sapiens ]
Official Symbol HIST1H2AC
Synonyms HIST1H2AC; histone cluster 1, H2ac; H2A histone family, member L , H2AFL, histone 1, H2ac; histone H2A type 1-C; histone H2AC; histone H2A/l; histone 1, H2ac; H2A histone family, member L; H2A/l; H2AFL; dJ221C16.4; MGC99519;
Gene ID 8334
mRNA Refseq NM_003512
Protein Refseq NP_003503
MIM 602794
UniProt ID Q93077
Chromosome Location 6p22.1
Pathway Amyloids, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem; Gene Expression, organism-specific biosystem; Meiosis, organism-specific biosystem;
Function DNA binding;

Not For Human Consumption!

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