Recombinant Human HGF protein, Fc-tagged

• Cat.No.: HGF-210H
• Product Overview: Recombinant Human HGF Protein is expressed from mammalian with a Fc Tag at the C-terminal. It contains Gln32-Ser728.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: Gln32-Ser728
• Description: Hepatocyte growth factor(HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.
• Form: Supplied as 0.22μm filtered solution in 20mM MES, 250mM Arginine, 150mM NaCl, 10% Glycerol, pH7.0 .
• Molecular Mass: The HGF single chain can be processed into the active form of disulfide-linked heterodimer of α and β chain.The protein has a predicted MW of 53.6 KDa (αchain)/51.7 KDa(βchain). Due to glycosylation, the protein migrates to 115, 65 and 60 kDa corresponding to the single chain,αchain and β chain based on Bis-Tris PAGE result.
• Endotoxin: Less than 1 EU per μg by the LAL method.
• Purity: >95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: HGF
• Official Symbol: HGF
• Synonyms: MET, AUTS9, HGFR, RCCP2, c-Met
• Gene ID: 3082
• mRNA Refseq: NM_000601.6
• Protein Refseq: NP_000592.3
• MIM: 142409
• UniProt ID: P14210