Recombinant Human Hepatocyte Growth Factor

• Cat.No.: HGF-627H
• Product Overview: Recombinant human HGF protein, was expressed in Insect cells and purified by using conventional chromatography.

Specification

• Species: Human
• Source: Human
• Tag: Non
• Description: Human Hepatocyte Growth Factor (HGF), also known as scatter factor, is a pleiotrophic cytokine that shows homology to the enzymes of the blood coagulation cascade. It stimulates the motility and invasion of several cancer cell types and can induce angiogenesis. Recently HGF was found to be identical to scatter factor, a fibroblast-derived factor promoting the dissociation of epithelial and vascular endothelial cell colonies in monolayer cell cultures by stimulating cell migration. HGF is synthesized as a biologically inactive single chain precursor, which is cleaved by a specific, extracellular serum serine protease to a fully active heterodimer.
• Form: Supplied lyophilized in 50 mM Acetic Acid. No stabilizer added.
• Purity: > 95% by SDS - PAGE
• Molecular Mass: 78.0 kDa
• Applications: Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
• Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: HGF hepatocyte growth factor (hepapoietin A; scatter factor) [ Homo sapiens ]
• Official Symbol: HGF
• Synonyms: HGF; hepatocyte growth factor (hepapoietin A; scatter factor); SF; HGFB; HPTA; F-TCF; DFNB39; hepatocyte growth factor; scatter factor; hepatopoietin A; OTTHUMP00000206710; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; deafness, autosomal recessive 39; Hepatopoeitin-A; Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain
• Gene ID: 3082
• mRNA Refseq: NM_000601
• Protein Refseq: NP_000592
• MIM: 142409
• UniProt ID: P14210
• Chromosome Location: 7q21.1
• Pathway: Cytokine-cytokine receptor; Focal adhesion; Melanoma; Pathways in cancer; Renal cell carcinoma; Hemostasis
• Function: catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; serine-type endopeptidase activity