Recombinant Human heat shock 70kDa protein 1A, His-tagged

• Cat.No.: HSPA1A-4851H
• Product Overview: Recombinant full-length human HSP70 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.

Specification

• Cat. No.: HSPA1A-4851H
• Description: HSP70 is a member of the heat shock protein family and is synthesized by cells of many organisms in response to stress. HSP70 is found mostly but not exclusively in the nucleus of unstressed cells. For several hours after a short heat shock, however, it is strongly concentrated in nucleoli. Nucleoli are transiently damaged by such a heat shock: their morphology changes and assembly and export of ribosomes is blocked for several hours.
• Applications: ATPase Assay; Western Blot
• Molecular Weight: 70 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50 mM sodium phosphate, PH 7.0, 300 mM NaCI, 150 mM imidazole, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >90%
• Concentration: 0.2 ug/ul
• Sequences: Full-length
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: Antigen processing and presentation; Antigen processing and presentation; Apoptosis Modulation by HSPA1A; Direct p53 effectors; Endocytosis; Influenza A; MAPK signaling pathway; Measles; Prion diseases; Protein processing in endoplasmic reticulum; Spliceosome; Toxoplasmosis; FOXM1 transcription factor network

Gene Information

• Gene Name: HSPA1A heat shock 70kDa protein 1A [ Homo sapiens ]
• Official Symbol: HSPA1A
• Synonyms: HSPA1A; heat shock 70kDa protein 1A; HSP72; HSPA1; HSPA1AI; HSPA1B; HSPA1A-1; FLJ54303; FLJ54370; FLJ54392; FLJ54408; FLJ75127; HSPA1A-1A; heat shock 70 kDa protein 1A/1B; HSPA1A-1/HSPA1A-2; HSPA1A.1/HSPA1A.2; OTTHUMP00000029287; heat shock 70kD protein 1A; heat shock-induced protein; heat shock 70 kDa protein 1/2; dnaK-type molecular chaperone HSPA1A-1
• Gene ID: 3303
• mRNA Refseq: NM_005345
• Protein Refseq: NP_005336
• MIM: 140550
• UniProt ID: P08107
• Chromosome Location: 6p21