Recombinant Human HDAC5 protein, GST-tagged

• Cat.No.: HDAC5-28267TH
• Product Overview: Recombinant Human full length HDAC5, fused with GST tag at N-terminal, was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 20% glycerol
• Bio-activity: ≥2500 pmol/min/µg.
• Molecular Mass: 150 kDa
• Purity: >8%
• Unit Definition: One U =1 pmol of acetyl group removed/min/µg of enzyme
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.04 mg/m

Gene Information

• Gene Name: HDAC5 histone deacetylase 5 [ Homo sapiens ]
• Official Symbol: HDAC5
• Synonyms: HDAC5; histone deacetylase 5; FLJ90614; KIAA0600; NY CO 9; antigen NY-CO-9; HD5; NY-CO-9
• Gene ID: 10014
• mRNA Refseq: NM_005474
• Protein Refseq: NP_005465
• MIM: 605315
• UniProt ID: Q9UQL6
• Chromosome Location: 17q21
• Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem
• Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); hydrolase activity; protein binding; protein kinase C binding; repressing transcription factor binding; transcription factor binding; contributes_to transcription regulatory region DNA binding