Recombinant Human HDAC11 protein, His-tagged
Cat.No. : | HDAC11-92H |
Product Overview : | Recombinant Human HDAC11(1-347 aa) fused with His tag at C-terminal was expressed in Insect cells. |
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Description : | This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. |
Source : | Insect cells |
Species : | Human |
Tag : | His |
Form : | Solution of purified recombinant protein in 50 mM Tris-HCl pH 7.5, 500 mM NaCl, 10% glycerol (w/v), 1 mM TCEP |
Molecular Mass : | 42.1 kDa |
Storage : | Store at -70 centigrade. Thaw quickly and store on ice before use. The remaining, unused, undiluted protein should be snap frozen, for example in a dry/ice ethanol bath or liquid nitrogen. Minimize freeze/thaws if possible, but very low volume aliquots (<5 µl) or storage of diluted protein is not recommended. |
Protein length : | 1-347 a.a. |
Gene Name | HDAC11 histone deacetylase 11 [ Homo sapiens ] |
Official Symbol | HDAC11 |
Synonyms | HDAC11; histone deacetylase 11; HD11; FLJ22237; |
Gene ID | 79885 |
mRNA Refseq | NM_024827 |
Protein Refseq | NP_079103 |
MIM | 607226 |
UniProt ID | Q96DB2 |
Chromosome Location | 3p25.1 |
Pathway | NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class II, organism-specific biosystem; |
Function | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; |
Not For Human Consumption!
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