Recombinant Human HBG2 protein, His-tagged

• Cat.No.: HBG2-16H
• Product Overview: Recombinant Human HBG2(1-147aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-147 a.a.
• Description: Hemoglobin subunit gamma-2, also known as HBG2, belongs to the fetal hemoglobin subunit, which consists of two alpha chains together with two gamma chains. Increased fetal hemoglobin production in adults can ameliorate the clinical severity of sickle cell disease and beta-thalassemia major.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol,1mM DTT
• Molecular Mass: 18.5 kDa (170aa) confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HBG2 hemoglobin subunit gamma 2 [ Homo sapiens ]
• Official Symbol: HBG2
• Synonyms: TNCY; HBG-T1; G-gamma globin Paulinia; abnormal hemoglobin; gamma-2-globin; hb F Ggamma; hemoglobin gamma-2 chain; hemoglobin gamma-G chain; hemoglobin, gamma G; methemoglobin
• Gene ID: 3048
• mRNA Refseq: NM_000184
• Protein Refseq: NP_000175
• MIM: 142250
• UniProt ID: P69892
• Chromosome Location: 11p15.5
• Pathway: Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: heme binding; iron ion binding; oxygen binding