Recombinant Human HBB Mutant (T87Q) Protein, Myc/DDK-tagged

• Cat.No.: HBB-059H
• Product Overview: Purified mutant recombinant protein of Human hemoglobin, beta (HBB), mutation at(T87Q) with a Myc/DDK tag was expressed in HEK293

Specification

• Description: The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 15.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: > 50 μg/mL as determined by microplate Bradford method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: HBB hemoglobin subunit beta [ Homo sapiens (human) ]
• Official Symbol: HBB
• Synonyms: HBB; hemoglobin subunit beta; ECYT6; CD113t-C; beta-globin; hemoglobin subunit beta; beta globin chain; hemoglobin beta subunit; hemoglobin, beta
• Gene ID: 3043
• mRNA Refseq: NM_000518
• Protein Refseq: NP_000509
• MIM: 141900
• UniProt ID: P68871