Recombinant Human HAP1 protein, His & GST-tagged
Cat.No. : | HAP1-1598H |
Product Overview : | Recombinant Human HAP1 aa. (Pro160~Gln381 (Accession # P54257)) fused with N-terminal His & GST tag was produced in E. coli cells. |
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Species : | Human |
Source : | E.coli |
Tag : | GST&His |
Protein Length : | Pro160~Gln381 |
Description : | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 55.9kDa |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 4.2 |
Gene Name | HAP1 huntingtin associated protein 1 [ Homo sapiens (human) ] |
Official Symbol | HAP1 |
Synonyms | HAP1; huntingtin associated protein 1; HLP; HAP2; HIP5; hHLP1; huntingtin-associated protein 1; HAP-1; huntingtin-associated protein 2; neuroan 1 |
Gene ID | 9001 |
mRNA Refseq | NM_001079870.1 |
Protein Refseq | NP_001073339.1 |
UniProt ID | P54257 |
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Not For Human Consumption!
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