Recombinant Human H2AB2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: H2AB2-6252H
• Product Overview: H2AFB2 MS Standard C13 and N15-labeled recombinant protein (NP_001017991) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy.
• Molecular Mass: 12.7 kDa
• AA Sequence: MPRRRRRRGSSGAGGRGRTCSRTVRAELSFSVSQVERSLREGHYAQRLSRTAPVYLAAVIEYLTAKVLELAGNEAQNSGERNITPLLLDMVVHNDRLLSTLFNTTTISQVAPGEDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: H2AB2 H2A.B variant histone 2 [ Homo sapiens (human) ]
• Official Symbol: H2AB2
• Synonyms: H2AB2; H2A.B variant histone 2; H2AB3; H2AFB2; H2A.Bbd; histone H2A-Bbd type 2/3; H2A Barr body deficient; H2A histone family member B2
• Gene ID: 474381
• mRNA Refseq: NM_001017991
• Protein Refseq: NP_001017991
• MIM: 301038
• UniProt ID: P0C5Z0