Recombinant Human GSDMB Protein, MYC/DDK-tagged

• Cat.No.: GSDMB-2354H
• Product Overview: Recombinant human GSDMB protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 47.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GSDMB gasdermin B [ Homo sapiens ]
• Official Symbol: GSDMB
• Synonyms: GSDML; PP4052; PRO2521
• Gene ID: 55876
• mRNA Refseq: NM_001042471
• Protein Refseq: NP_001035936
• MIM: 611221
• UniProt ID: Q8TAX9