Recombinant Human GSC2 Protein, His-tagged

• Cat.No.: GSC2-2356H
• Product Overview: Recombinant human GSC2 protein, fused to His-tagged at N-terminus, was expressed in E. coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 21.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GSC2 goosecoid homeobox 2 [ Homo sapiens ]
• Official Symbol: GSC2
• Synonyms: GSCL; GSCL
• Gene ID: 2928
• mRNA Refseq: NM_005315
• Protein Refseq: NP_005306
• MIM: 601845
• UniProt ID: O15499