Recombinant Human GRB7, His-tagged

• Cat.No.: GRB7-13521H
• Product Overview: Recombinant Human GRB7 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 184-532a.a.
• Description: This gene encodes a protein with G-patch and KOW domains which are involved in RNA binding. The encoded protein may be orthologous to the Arabidopsis protein, modifier of snc 1, 2, which contains the same domains and is required for innate resistance to some pathogens (PMID: 16271871).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GRB7 growth factor receptor-bound protein 7 [ Homo sapiens ]
• Official Symbol: GRB7
• Synonyms: GRB7; growth factor receptor-bound protein 7; B47; GRB7 adapter protein; epidermal growth factor receptor GRB-7
• Gene ID: 2886
• mRNA Refseq: NM_001030002
• Protein Refseq: NP_001025173
• MIM: 601522
• UniProt ID: Q14451
• Chromosome Location: 17q12
• Pathway: Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; EPHB forward signaling, organism-specific biosystem; GRB7 events in ERBB2 signaling, organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: RNA binding; SH3/SH2 adaptor activity; identical protein binding; lipid binding; phosphatidylinositol binding; protein binding; protein kinase binding