Recombinant Human GPR75 Protein (M1-V540 end), eGFP, 10×His tagged

• Cat.No.: GPR75-0493H
• Product Overview: Recombinant Human HA(signal peptide)-Flag-GPR75(M1-V540 end)-3C-eGFP-10His Protein was expressed in Mammalian cell.

Specification

• Description: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
• Source: Mammalian cell
• Species: Human
• Tag: His&EGFP
• Form: Liquid
• Protein length: M1-V540 end
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 60%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 20 mM HEPES pH 7.5, 200 mM NaCl, 1.5% glycerol, 5 mM EDTA, 0.01% (w/v)LMNG, and 0.001% (w/v)CHS
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: GPR75 G protein-coupled receptor 75 [ Homo sapiens (human) ]
• Official Symbol: GPR75
• Synonyms: GPR75; G protein-coupled receptor 75; probable G-protein coupled receptor 75; WI 31133; GPRchr2; WI31133; MGC132002
• Gene ID: 10936
• mRNA Refseq: NM_006794
• Protein Refseq: NP_006785
• MIM: 606704
• UniProt ID: O95800