Recombinant Human GPLD1 Protein, DYKDDDDK-tagged

• Cat.No.: GPLD1-01H
• Product Overview: Recombinant protein from the full-length sequence of homo sapiens glycosylphosphatidylinositol specific phospholipase D1 (GPLD1) (NM_001503), with a DYKDDDDK tag was expressed in human cells.

Specification

• Description: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.
• Source: Human Cells
• Species: Human
• Tag: Flag
• Molecular Mass: 89.8 kDa
• Endotoxin: < 0.1 ng/μg of protein (<1 EU/μg)
• Purity: > 90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Gene Information

• Gene Name: GPLD1 glycosylphosphatidylinositol specific phospholipase D1 [ Homo sapiens (human) ]
• Official Symbol: GPLD1
• Synonyms: GPLD1; glycosylphosphatidylinositol specific phospholipase D1; PLD; GPIPLD; PIGPLD; GPIPLDM; PIGPLD1; phosphatidylinositol-glycan-specific phospholipase D; GPI-PLD; GPI-specific phospholipase D; PI-G PLD; glycoprotein phospholipase D; EC 3.1.4.50
• Gene ID: 2822
• mRNA Refseq: NM_001503
• Protein Refseq: NP_001494
• MIM: 602515
• UniProt ID: P80108

Reviews

12/29/2022

Swift and accurate service, essential for research progress.

10/20/2022

Invaluable support for insights, a research necessity.

09/23/2021

Trustworthy results, accelerates our research success.

Q&As

How does GPLD1 interact with other enzymes in carbohydrate and lipid metabolism?

GPLD1 works with other metabolic enzymes, coordinating carbohydrate and lipid metabolism.

What potential therapeutic applications arise from targeting GPLD1 in metabolic diseases?

Targeting GPLD1 offers potential in treating metabolic disorders by regulating liver metabolism.

What role does GPLD1 play in lipid metabolism?

GPLD1 is also involved in lipid metabolism, affecting fat processing and storage.

What is the impact of altered GPLD1 activity on metabolic disorders?

Altered GPLD1 activity is linked to various metabolic disorders, including diabetes and liver diseases.

What is the primary role of GPLD1 in liver function?

GPLD1, a glycosylphosphatidylinositol-specific phospholipase, is involved in modulating liver metabolism and function.

How do genetic variations in GPLD1 affect liver health?

Genetic variations in GPLD1 can lead to altered metabolic processing, impacting liver health and function.

How does GPLD1 contribute to glycogen metabolism?

It plays a role in glycogen metabolism, impacting glucose regulation in the liver.