Recombinant Human GP6 protein, His-tagged

• Cat.No.: GP6-1950H
• Product Overview: Recombinant Human GP6 aa. (Tyr86~Thr231 (Accession # Q9HCN6)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Tyr86~Thr231
• Description: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: Freeze-dried powder
• Molecular Mass: 19kDa as determined by
  SDS-PAGE reducing conditions
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Characteristic: The isoelectric point is 5.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: GP6 glycoprotein VI platelet [ Homo sapiens (human) ]
• Official Symbol: GP6
• Synonyms: MYH5; MHC20; MYH16P; myosin heavy polypeptide 5; myosin, heavy chain 16; myosin, heavy polypeptide 16; sarcomeric myosin
• Gene ID: 51206
• mRNA Refseq: NM_001083899.2
• Protein Refseq: NP_001077368.2
• UniProt ID: Q9HCN6