Recombinant Human GNAS/GNB1 Protein, 8×His-tagged

• Cat.No.: GNAS/GNB1-1642H
• Product Overview: Recombinant Human GNAS(M1-L394 end) (S54N, G226A, E268A, N271K, K274D, R280K, T284D, I285T)/8His-TEV-GNB1(M1-N340 end) protein with a 8×His was expressed in Insect cell

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• ProteinLength: 1-394;1-340 a.a.
• Description: Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor This protein is produced by a bicistronic gene which also produces the ALEX protein from an overlapping reading frame. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 70%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 10 mM HEPES pH 7.5, 100 mM NaCl, 10% glycerol, 1 mM MgCl2, 1 μM GDP, 0.1 mM TCEP
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: GNAS GNAS complex locus [ Homo sapiens (human) ]
• Official Symbol: GNAS
• Synonyms: Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor
• Gene ID: 2778
• mRNA Refseq: NM_000516
• Protein Refseq: NP_000507
• MIM: 139320
• UniProt ID: P63092