Recombinant Human Glycogen Synthase Kinase 3 Alpha, His-tagged

• Cat.No.: GSK3A-1234H
• Product Overview: Recombinant humanfull length GSK3A, His-tagged.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: GSK3Ais a multifunctional protein serine/threonine kinase implicated in thecontrol of several regulatory proteins and transcription factors.
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.5 mM EGTA + 0.05% NP-40 + 5 mMDTT + 50% glycerol.
• Molecular Weight: 53.7 kDa
• Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: GSK3A
• Full Length: Full L.

Gene Information

• Gene Name: GSK3A glycogen synthase kinase 3alpha [ Homo sapiens ]
• Synonyms: GSK3A; glycogen synthase kinase3 alpha; DKFZp686D0638; Glycogen synthase kinase-3 alpha; GSK-3 alpha; EC 2.7.11.26
• Gene ID: 2931
• mRNA Refseq: NM_019884
• Protein Refseq: NP_063937
• MIM: 606784
• UniProt ID: P49840
• Chromosome Location: 19q13
• Pathway: AKT phosphorylates targets in the cytosol; Activationof Chaperones by IRE1alpha; B Cell Receptor Signaling Pathway; Chemokinesignaling pathway; Diabetes pathways; Dopaminergic synapse; Downstream signaltransduction; FOXM1 transcription factor network; GAB1 signalosome; GlycogenMetabolism; IL-3 Signaling Pathway; IL-5 Signaling Pathway; Insulin Signaling;PI-3K cascade; PI3K/AKT activation; PIP3 activates AKT signaling
• Function: ATP binding; protein binding;nucleotide binding; transferase activity; glycogen synthase kinase 3activity; protein kinase A catalytic subunit binding; tau-protein kinaseactivity