Recombinant Human GLUD2, His-tagged

• Cat.No.: GLUD2-27654TH
• Product Overview: Recombinant fragment, corresponding to amino acids 229-541 of Human GLUD2 with N terminal His tag; 313 amino acids, 36kDa.

Specification

• Description: The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 89 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Store at 4°C. Upon reconstitution store at -80oC.
• Sequences of amino acids: GEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGR ISATGRGVFHGIENFINEASYMSILGMTPGFRDKTFVV QGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPK ELEDFKLQHGSILGFPKAKPYEGSILEVDCDILIPAAT EKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNI LVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDS NYHLLLSVQESLERKFGKHGGTIPIVPTAEFQDSISGA SEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYVN
• Protein length: 229-541 a.a.

Gene Information

• Gene Name: GLUD2 glutamate dehydrogenase 2 [ Homo sapiens ]
• Official Symbol: GLUD2
• Synonyms: GLUD2; glutamate dehydrogenase 2; GLUDP1, glutamate dehydrogenase pseudogene 1; glutamate dehydrogenase 2, mitochondrial
• Gene ID: 2747
• mRNA Refseq: NM_012084
• Protein Refseq: NP_036216
• MIM: 300144
• Uniprot ID: P49448
• Chromosome Location: Xq24-q25
• Pathway: Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; D-Glutamine and D-glutamate metabolism, organism-specific biosystem
• Function: ADP binding; GTP binding; glutamate dehydrogenase (NAD+) activity; glutamate dehydrogenase [NAD(P)+] activity; leucine binding