Recombinant Human GKN2 protein, His-tagged

• Cat.No.: GKN2-1610H
• Product Overview: Recombinant Human GKN2 aa. (Tyr21~Val184 (Accession # Q86XP6)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 23kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Tyr21~Val184
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 6.6

Gene Information

• Gene Name: GKN2 gastrokine 2 [ Homo sapiens (human) ]
• Official Symbol: GKN2
• Synonyms: GKN2; gastrokine 2; GDDR; TFIZ1; PRO813; BRICD1B; VLTI465; gastrokine-2; BRICHOS domain containing 1B; blottin; down-regulated in gastric cancer GDDR; trefoil factor interactions(z) 1
• Gene ID: 200504
• mRNA Refseq: NM_182536.2
• Protein Refseq: NP_872342.2
• UniProt ID: Q86XP6