Recombinant Human GIPC2, GST-tagged

• Cat.No.: GIPC2-13266H
• Product Overview: Recombinant Human GIPC2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-315a.a.
• Description: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GIPC2 GIPC PDZ domain containing family, member 2 [ Homo sapiens ]
• Official Symbol: GIPC2
• Synonyms: GIPC2; GIPC PDZ domain containing family, member 2; PDZ domain-containing protein GIPC2; FLJ20075; semaphorin cytoplasmic domain associated protein 2; SEMCAP 2; PDZ domain protein GIPC2; semaF cytoplasmic domain associated protein 2; SEMCAP2; SEMCAP-2
• Gene ID: 54810
• mRNA Refseq: NM_017655
• Protein Refseq: NP_060125
• UniProt ID: Q8TF65
• Chromosome Location: 1p31.1