Recombinant Human GIP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GIP-4581H
• Product Overview: GIP MS Standard C13 and N15-labeled recombinant protein (NP_004114) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
• Molecular Mass: 17.1 kDa
• AA Sequence: MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQREARALELAGQANRKEEEAVEPQSSPAKNPSDEDLLRDLLIQELLACLLDQTNLCRLRSRTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GIP gastric inhibitory polypeptide [ Homo sapiens (human) ]
• Official Symbol: GIP
• Synonyms: GIP; gastric inhibitory polypeptide; glucose dependent insulinotropic polypeptide; glucose-dependent insulinotropic polypeptide
• Gene ID: 2695
• mRNA Refseq: NM_004123
• Protein Refseq: NP_004114
• MIM: 137240
• UniProt ID: P09681