Recombinant Human GGCT, His-tagged

• Cat.No.: GGCT-13239H
• Product Overview: Recombinant Human GGCT protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 1-188a.a.
• Description: Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GGCT gamma-glutamylcyclotransferase [ Homo sapiens ]
• Official Symbol: GGCT
• Synonyms: GGCT; gamma-glutamylcyclotransferase; C7orf24, chromosome 7 open reading frame 24 , GCTG; CRF21; Ggc; MGC3077; cytochrome c-releasing factor 21; gamma -glutamyl cyclotransferase; GGC; GCTG; C7orf24; FLJ11717
• Gene ID: 79017
• mRNA Refseq: NM_001199815
• Protein Refseq: NP_001186744
• MIM: 137170
• UniProt ID: O75223
• Chromosome Location: 7p15-p14
• Pathway: Biological oxidations, organism-specific biosystem; Glutathione conjugation, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Glutathione synthesis and recycling, organism-specific biosystem; Metabolism, organism-specific biosystem; Phase II conjugation, organism-specific biosystem
• Function: gamma-glutamylcyclotransferase activity; gamma-glutamylcyclotransferase activity; protein homodimerization activity; transferase activity, transferring acyl groups