Recombinant Human GGACT, His-tagged

• Cat.No.: GGACT-7728H
• Product Overview: Recombinant Human gammaGlutamylaminecyclotransferase/A2LD1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1Arg153) of Human A2LD1 fused with a His tag at the Cterminus.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: GammaGlutamylaminecyclotransferase is an enzyme that converts gammaglutamylamines to free amines and 5oxoproline which belongs to the gammaglutamylcyclotransferase family. It shows high activity toward gammaglutamylepsilonlysine, derived from the breakdown of fibrin and contributes to degradation of proteins crosslinked by transglutaminases. It degrades the crosslink between a lysine and a glutamic acid residue from two proteins that have been crosslinked by transglutaminases. This protein adopts the newly identified cyclotransferase fold, observed in GammaGlutamylcyclotransferase, an enzyme with activity toward gammaglutamylalphaamino acids.
• Form: Supplied as a 0.2 μM filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MALVFVYGTL KRGQPNHRVL RDGAHGSAAF RARGRTLEPY PLVIAGEHN IPWLLHLPGS GRLVEGEVYA VDERMLRFLD DFESCPALYQ RTVLRVQLLE D RAPGAEEP PAPTAVQCFV YSRATFPPEW AQLPHHDSYD SEGPHGLRYN PRENR*
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Notes: For research use only.
• Storage: Store at less than 20°C. stable for 6 months after receipt.Please minimize freezethaw cycles.

Gene Information

• Gene Name: GGACT gamma-glutamylamine cyclotransferase [ Homo sapiens ]
• Official Symbol: GGACT
• Synonyms: GGACT; gamma-glutamylamine cyclotransferase; RP11-151A6.2, A2LD1
• Gene ID: 87769
• MIM: 613378
• UniProt ID: Q9BVM4
• Chromosome Location: 13q32.3
• Function: gamma-glutamylcyclotransferase activity