Recombinant Human GGA1, His-tagged

• Cat.No.: GGA1-28744TH
• Product Overview: Recombinant fragment, corresponding to amino acids 162-639 of Human GGA1 with an N-terminal His Tag, 478 amino acids, approximately 88kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 162-639 a.a.
• Description: This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Conjugation: HIS
• Form: Lyophilised:reconstitution with 101 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium hydrogen phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: PRPKNVIFEDEEKSKMLARLLKSSHPEDLRAANKLIKEMV QEDQKRMEKISKRVNAIEEVNNNVKLLTEMVMSHSQGG AAAGSSEDLMKELYQRCERMRPTLFRLASDTEDNDEALAE ILQANDNLTQVINLYKQLVRGEEVNGDATAGSIPGSTS ALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVS LLDDELMSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPA PALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQ SLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPSN ILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLS TAPQPIRNIVFQSAVPKVMKVKLQPPSGTELPAFNPIVHP SAITQVLLLANPQKEKVRLRYKLTFTMGDQTYNEMGDV DQFPPPETWGSL

Gene Information

• Gene Name: GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 [ Homo sapiens ]
• Official Symbol: GGA1
• Synonyms: GGA1; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; ADP-ribosylation factor-binding protein GGA1
• Gene ID: 26088
• mRNA Refseq: NM_001001560
• Protein Refseq: NP_001001560
• MIM: 606004
• Uniprot ID: Q9UJY5
• Chromosome Location: 22q13.31
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: molecular_function; protein binding