Recombinant Human GFAP protein, MYC/DDK-tagged
Cat.No. : | GFAP-20H |
Product Overview : | Recombinant Human GFAP, transcript variant 1, fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells. |
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Description : | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Source : | HEK293 cells |
Species : | Human |
Tag : | Myc&DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 49.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Protein length : | 1-432 aa |
Gene Name | GFAP glial fibrillary acidic protein [ Homo sapiens ] |
Official Symbol | GFAP |
Synonyms | ALXDRD; glial fibrillary acidic protein |
Gene ID | 2670 |
mRNA Refseq | NM_002055 |
Protein Refseq | NP_002046 |
MIM | 137780 |
UniProt ID | P14136 |
Chromosome Location | 17q21 |
Pathway | Neural Crest Differentiation, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Signal Transduction, organism-specific biosystem |
Function | integrin binding; kinase binding; protein binding |
Not For Human Consumption!
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