Recombinant Human GEMIN6, His-tagged

• Cat.No.: GEMIN6-7560H
• Product Overview: Recombinant human GEMIN6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex includes SMN, GEMIN2, GEMIN3, GEMIN4, and GEMIN5.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
• Molecular Mass: 21.9 kDa (190aa) confirmed by MALDI-TOF
• Protein length: 1-167aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEWMKK GPLEWQDYIY KEVRVTASEK NEYKGWVLTT DPVSANIVLV NFLEDGSMSV TGIMGHAVQT VETMNEGDHR VREKLMHLFT SGDCKAYSPE DLEERKNSLK KWLEKNHIPI TEQGDAPRTL CVAGVLTIDP PYGPENCSSS NEIILSRVQD LIEGHLTASQ
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml

Gene Information

• Gene Name: GEMIN6 gem (nuclear organelle) associated protein 6 [ Homo sapiens ]
• Official Symbol: GEMIN6
• Synonyms: GEMIN6; gem (nuclear organelle) associated protein 6; gem-associated protein 6; FLJ23459; SIP2; gemin 6; gemin-6
• Gene ID: 79833
• mRNA Refseq: NM_024775
• Protein Refseq: NP_079051
• MIM: 607006
• UniProt ID: Q8WXD5
• Chromosome Location: 2p22.1
• Pathway: Gene Expression, organism-specific biosystem; Metabolism of non-coding RNA, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Survival motor neuron (SMN) complex, organism-specific biosystem; snRNP Assembly, organism-specific biosystem
• Function: protein binding