Recombinant Human GDNF Protein

• Cat.No.: GDNF-708H
• Product Overview: Recombinant human GDNF protein was expressed from CHO-based cell line and purified by QMCF Technology.

Specification

• Species: Human
• Source: CHO
• Tag: Non
• Description: GDNF is an important member of the GDNF family of ligands. Four members of nurotrophic factors beloning to the GDNF family of ligands : glial cell line-derived neurotrophic factor (GDNF), neurturin (NRTN), artemin (ARTN), and persephin (PSPN). GDNF is important in the promotion of the survival of dopaminergic neurons. The recombinant form of this protein promotes the survival and differentiation of dopaminergic neurons in culture, and is able to prevent apoptosis of motor neurons induced by axotomy.
• Form: PBS pH 7.4.
• Molecular Mass: Mature GDNF, Approximately 15 kDa, a single non-glycosylated polypeptide chain containing 118 amino acids.
• Endotoxin: Less than 1EU/mg of protein as determined by LAL method.
• Storage: Store at -70 centigrade upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: glial cell derived neurotrophic factor
• Official Symbol: GDNF
• Synonyms: Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor (ATF)
• Gene ID: 2668
• mRNA Refseq: NM_000514.3
• Protein Refseq: NP_000505.1
• MIM: 66837
• UniProt ID: P39905