Recombinant Human GDF11 Protein
| Cat.No. : | GDF11-155H |
| Product Overview : | Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed. |
- Specification
- Gene Information
- Related Products
- Download
| Description : | Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development. |
| Source : | Human Cells |
| Species : | Human |
| Form : | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
| AA Sequence : | Asn299-Ser407 |
| Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
| Purity : | >95% |
| Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. |
| Reconstitution : | It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Quality Statement : | Purity: greater than 95% as determined by reducing SDS-PAGE. |
| Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Protein length : | 299-407 a.a. |
| Gene Name | GDF11 growth differentiation factor 11 [ Homo sapiens (human) ] |
| Official Symbol | GDF11 |
| Synonyms | Growth/differentiation factor 11; GDF-11; Bone morphogenetic protein 11; BMP-11; VHO; BMP11 |
| Gene ID | 10220 |
| mRNA Refseq | NM_005811.5 |
| Protein Refseq | NP_005802.1 |
| MIM | 603936 |
| UniProt ID | O95390 |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All GDF11 Products
Required fields are marked with *
My Review for All GDF11 Products
Required fields are marked with *
0
Inquiry Basket
