Recombinant Human GDE1, GST-tagged

• Cat.No.: GDE1-13206H
• Product Overview: Recombinant Human GDE1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• ProteinLength: 1-331a.a.
• Description: Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GDE1 glycerophosphodiester phosphodiesterase 1 [ Homo sapiens ]
• Official Symbol: GDE1
• Synonyms: GDE1; glycerophosphodiester phosphodiesterase 1; membrane interacting protein of RGS16; MIR16; RGS16-interacting membrane protein; membrane-interacting protein of RGS16; 363E6.2
• Gene ID: 51573
• mRNA Refseq: NM_016641
• Protein Refseq: NP_057725
• MIM: 605943
• UniProt ID: Q9NZC3
• Chromosome Location: 16p12-p11.2
• Function: glycerophosphodiester phosphodiesterase activity; glycerophosphoinositol glycerophosphodiesterase activity; hydrolase activity; metal ion binding