Recombinant Human GBP5, GST-tagged

• Cat.No.: GBP5-13183H
• Product Overview: Recombinant Human GBP5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 382-586a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GBP5 guanylate binding protein 5 [ Homo sapiens ]
• Official Symbol: GBP5
• Synonyms: GBP5; guanylate binding protein 5; guanylate-binding protein 5; GBP-TA antigen; GTP-binding protein 5; guanine nucleotide-binding protein 5; GBP-5
• Gene ID: 115362
• mRNA Refseq: NM_001134486
• Protein Refseq: NP_001127958
• MIM: 611467
• UniProt ID: Q96PP8
• Chromosome Location: 1p22.2
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding