Recombinant Human GBA2 Protein, MYC/DDK-tagged

• Cat.No.: GBA2-129H
• Product Overview: Recombinant Human GBA2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 104.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GBA2 glucosidase, beta (bile acid) 2 [ Homo sapiens ]
• Official Symbol: GBA2
• Synonyms: GBA2; glucosidase, beta (bile acid) 2; non-lysosomal glucosylceramidase; AD035; bile acid beta glucosidase; DKFZp762K054; KIAA1605; non lysosomal glucosylceramidase; NLGase; beta-glucosidase 2; glucosylceramidase 2; beta-glucocerebrosidase 2; bile acid beta-glucosidase; MGC16895
• Gene ID: 57704
• mRNA Refseq: NM_020944
• Protein Refseq: NP_065995
• MIM: 609471
• UniProt ID: Q9HCG7