Recombinant Human GART Protein, MYC/DDK-tagged

• Cat.No.: GART-26H
• Product Overview: Recombinant Human GART was expressed in HEK293 with C-terminal MYC/DDK tag.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 45.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [ Homo sapiens (human) ]
• Official Symbol: GART
• Synonyms: AIRS; GARS; PAIS; PGFT; PRGS; GARTF
• Gene ID: 2618
• mRNA Refseq: NM_175085
• Protein Refseq: NP_780294
• MIM: 138440
• UniProt ID: P22102