GART
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Official Full Name
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -
Overview
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. -
Synonyms
GART;phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase;PGFT, PRGS;trifunctional purine biosynthetic protein adenosine-3;AIRS;GARS;PAIS;PGFT;PRGS;GARTF;MGC47764
Recombinant Proteins
- Chicken
- Human
- Mouse
- Zebrafish
- Mammalian Cells
- HEK293
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GART-1112C | Recombinant Chicken GART | Mammalian Cells | Chicken | His |
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| GART-26H | Recombinant Human GART Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| GART-6212M | Recombinant Mouse GART Protein | Mammalian Cells | Mouse | His |
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| GART-9156Z | Recombinant Zebrafish GART | Mammalian Cells | Zebrafish | His |
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| GART-687HCL | Recombinant Human GART cell lysate | Human | Non |
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| Gart-3155M | Recombinant Mouse Gart Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| GART-3471M | Recombinant Mouse GART Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GART-3471M-B | Recombinant Mouse GART Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GART-4265H | Recombinant Human GART protein, His-tagged | E.coli | Human | His | 111–318aa |
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| GART-4732H | Recombinant Human GART Protein, GST-tagged | Wheat Germ | Human | GST |
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| GART-5447HF | Recombinant Full Length Human GART Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 433 amino acids |
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Involved Pathway
GART involved in several pathways and played different roles in them. We selected most pathways GART participated on our site, such as Purine metabolism,One carbon pool by folate,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GART were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | DEGS1,COX5AA,EXT2,PIGP,PRPS1A,POLR2G,ADI1,PCYT1A,CYP11C1,ALPI.2 |
| Purine metabolism | PAICS,PNP,IMPDH1B,TM9SF1,PGM2,PDE6A,POLR2F,PAPSS2A,ZNRD1,PDE3B |
| One carbon pool by folate | TYMS,MTHFD2L,MTFMT,ATIC,ST20-MTHFS,DHFRL1,ALDH1L2,SHMT1,FTCD,MTHFD1B |
Protein Function
GART has several biochemical functions, for example, ATP binding,metal ion binding,methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GART itself. We selected most functions GART had, and list some proteins which have the same functions with GART. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | GRK1,ATP13A5,TTLL9,ABCG2B,CDKL2,MYO19,VSIG8B,DYRK4,EPHB2,SYN2 |
| methyltransferase activity | EHMT1B,PRDM14,SMYD1B,SETDB1A,KIAA1456,ALDH1L1,TOMT,FAM119B,METTL21D,METTL18 |
| metal ion binding | ZBTB16,NR5A1A,LNPA,ZNF362A,CYP4F18,SCAPER,SH3RF3,CACNA1H,KLF14,ACVR1 |
Interacting Protein
GART has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GART here. Most of them are supplied by our site. Hope this information will be useful for your research of GART.
ARF6;IKBKG;PXN;KPNA2;acuC;15-deoxy-delta(12,14;FN1;VCAM1;Bmpr1a;NES;PPIA;VP35;NCBP1;DBN1;ATL3;Myh9;Bag2;MYO19
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