Recombinant Human GADD45A, His-tagged

Cat.No. : GADD45A-26075TH
Product Overview : Recombinant full length Human GADD45A with C terminal His tag; 173 amino acids with tag, MWt 19.4kDa.
  • Specification
  • Gene Information
  • Related Products
  • Download
Species : Human
Source : E.coli
Tag : His
Description : This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Conjugation : HIS
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPERLEHHH HHH
Sequence Similarities : Belongs to the GADD45 family.
Full Length : Full L.
Gene Name GADD45A growth arrest and DNA-damage-inducible, alpha [ Homo sapiens ]
Official Symbol GADD45A
Synonyms GADD45A; growth arrest and DNA-damage-inducible, alpha; DDIT1; growth arrest and DNA damage-inducible protein GADD45 alpha; GADD45;
Gene ID 1647
mRNA Refseq NM_001199741
Protein Refseq NP_001186670
MIM 126335
Uniprot ID P24522
Chromosome Location 1p31.2
Pathway ATF-2 transcription factor network, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem;
Function protein binding;

Not For Human Consumption!

Inquiry

  • Reviews
  • Q&As

Customer Reviews (0)

Write a review

Q&As (0)

Ask a question

Ask a Question for All GADD45A Products

Required fields are marked with *

My Review for All GADD45A Products

Required fields are marked with *

0

Inquiry Basket

cartIcon