Recombinant Human GADD45A, His-tagged
Cat.No. : | GADD45A-26075TH |
Product Overview : | Recombinant full length Human GADD45A with C terminal His tag; 173 amino acids with tag, MWt 19.4kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Conjugation : | HIS |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPERLEHHH HHH |
Sequence Similarities : | Belongs to the GADD45 family. |
Full Length : | Full L. |
Gene Name | GADD45A growth arrest and DNA-damage-inducible, alpha [ Homo sapiens ] |
Official Symbol | GADD45A |
Synonyms | GADD45A; growth arrest and DNA-damage-inducible, alpha; DDIT1; growth arrest and DNA damage-inducible protein GADD45 alpha; GADD45; |
Gene ID | 1647 |
mRNA Refseq | NM_001199741 |
Protein Refseq | NP_001186670 |
MIM | 126335 |
Uniprot ID | P24522 |
Chromosome Location | 1p31.2 |
Pathway | ATF-2 transcription factor network, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; |
Function | protein binding; |
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◆ Cell & Tissue Lysates | ||
GADD45A-575HCL | Recombinant Human GADD45A cell lysate | +Inquiry |
Not For Human Consumption!
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