Recombinant Human GABRA2 Protein, His/GST-tagged

• Cat.No.: GABRA2-388H
• Product Overview: Recombinant Human GABRA2(Phe42~Ile250) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Phe42~Ile250
• Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 54.1kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 [ Homo sapiens ]
• Official Symbol: GABRA2
• Synonyms: GABRA2; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid receptor subunit alpha-2; GABA(A) receptor; alpha 2; GABA(A) receptor, alpha 2; GABA(A) receptor subunit alpha-2; FLJ97076
• Gene ID: 2555
• mRNA Refseq: NM_000807
• Protein Refseq: NP_000798
• MIM: 137140
• UniProt ID: P47869