Recombinant Human GABBR1 protein, His & T7-tagged

• Cat.No.: GABBR1-8161H
• Product Overview: Recombinant Human GABBR1 aa. (Val199~Gly570 (Accession# Q9UBS5)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Val199~Gly570
• Description: This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 46.1kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Characteristic: The isoelectric point is 7.2.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in ddH2O.

Gene Information

• Gene Name: GABBR1 gamma-aminobutyric acid type B receptor subunit 1 [ Homo sapiens (human) ]
• Official Symbol: GABBR1
• Synonyms: GB1; GPRC3A; GABABR1; GABBR1-3; GABA-B receptor, R1 subunit; gamma-aminobutyric acid (GABA) B receptor, 1; seven transmembrane helix receptor; gamma-aminobutyric acid type B receptor subunit 1
• Gene ID: 2550
• mRNA Refseq: NM_001319053.1
• Protein Refseq: NP_001305982.1
• UniProt ID: Q9UBS5