Recombinant Human G3BP1, GST-tagged

• Cat.No.: G3BP1-13076H
• Product Overview: Recombinant Human G3BP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-300a.a.
• Description: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: G3BP1 GTPase activating protein (SH3 domain) binding protein 1 [ Homo sapiens ]
• Official Symbol: G3BP1
• Synonyms: G3BP1; GTPase activating protein (SH3 domain) binding protein 1; ras GTPase-activating protein-binding protein 1; G3BP; HDH VIII; Ras GTPase activating protein SH3 domain binding protein; G3BP-1; GAP binding protein; ATP-dependent DNA helicase VIII; GAP SH3 domain-binding protein 1; RasGAP-associated endoribonuclease G3BP; Ras-GTPase-activating protein SH3-domain-binding protein; HDH-VIII; MGC111040
• Gene ID: 10146
• mRNA Refseq: NM_005754
• Protein Refseq: NP_005745
• MIM: 608431
• UniProt ID: Q13283
• Chromosome Location: 5q33.1
• Function: ATP binding; ATP-dependent DNA helicase activity; ATP-dependent RNA helicase activity; DNA binding; RNA binding; endonuclease activity; helicase activity; hydrolase activity; nucleotide binding; protein binding