Recombinant Human G Protein-Coupled Receptor Kinase 6, GST-tagged
Cat.No. : | GRK6-1020H |
Product Overview : | Full-length recombinant human GRK6 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | Sf9 Cells |
Tag : | GST |
Description : | GRK6 is a Ser/Thr protein kinase and a member of the G protein-coupled receptor kinase subfamily. GRK6 is present in all tissues with strongest expression in placenta and skeletal muscle. GRK6 can phosphorylate proteins such as rhodopsin, ADRB2 and the leukotriene B4 receptor BLT1. GRK6 phosphorylates G protein-coupled dopamine receptors, thereby regulating their activity and mediating desensitization of the receptors. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 93 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Form : | Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | >80% |
Concentration : | 0.1 ug/ul |
Specific Activity : | 11 nmol/min/mg |
Sequences : | Full length |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | CXCR4-mediated signaling events; Chemokine signaling pathway; Chemokine signaling pathway; Endocytosis; Myometrial Relaxation and Contraction Pathways |
Gene Name | GRK6 G protein-coupled receptor kinase 6 [ Homo sapiens ] |
Official Symbol | GRK6 |
Synonyms | GRK6; G protein-coupled receptor kinase 6; GPRK6; FLJ32135; G protein-coupled receptor kinase 6; OTTHUMP00000223834; OTTHUMP00000223835; OTTHUMP00000223836; OTTHUMP00000231482; OTTHUMP00000231483; g protein-coupled receptor kinase GRK6 |
Gene ID | 2870 |
mRNA Refseq | NM_001004105 |
Protein Refseq | NP_001004105 |
MIM | 600869 |
UniProt ID | P43250 |
Chromosome Location | 5q35 |
Function | ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; signal transducer activity |
◆ Recombinant Proteins | ||
GRK6-5358H | Recombinant Human GRK6 Protein, GST-tagged | +Inquiry |
GRK6-393H | Recombinant Human GRK6 Protein, His-tagged | +Inquiry |
GRK6-2446HF | Active Recombinant Full Length Human GRK6 Protein | +Inquiry |
GRK6-13542H | Recombinant Human GRK6, GST-tagged | +Inquiry |
GRK6-5548HF | Recombinant Full Length Human GRK6 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
GRK6-622HCL | Recombinant Human GRK6 cell lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All GRK6 Products
Required fields are marked with *
My Review for All GRK6 Products
Required fields are marked with *
0
Inquiry Basket