Recombinant Human FUK, His-tagged

• Cat.No.: FUK-13033H
• Product Overview: Recombinant Human FUK protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 695-1084a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FUK fucokinase [ Homo sapiens ]
• Official Symbol: FUK
• Synonyms: FUK; fucokinase; L-fucose kinase; FLJ39408; L fucose kinase; 1110046B12Rik
• Gene ID: 197258
• mRNA Refseq: NM_145059
• Protein Refseq: NP_659496
• MIM: 608675
• UniProt ID: Q8N0W3
• Chromosome Location: 16q22.1
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; GDP-L-fucose biosynthesis II (from L-fucose), organism-specific biosystem; Metabolic pathways, organism-specific biosystem
• Function: ATP binding; fucokinase activity; nucleotide binding