Recombinant Human FSCN2 protein, His-tagged

• Cat.No.: FSCN2-1278H
• Product Overview: Recombinant Human FSCN2 aa. (Gln8~His258 (Accession # O14926) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Gln8~His258
• Description: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: 29kDa as determined by SDS-PAGE reducing conditions.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: FSCN2 fascin actin-bundling protein 2, retinal [ Homo sapiens (human) ]
• Official Symbol: FSCN2
• Synonyms: FSCN2; fascin actin-bundling protein 2, retinal; RFSN; RP30; fascin-2; fascin homolog 2, actin-bundling protein, retinal
• Gene ID: 25794
• mRNA Refseq: NM_001077182.2
• Protein Refseq: NP_001070650.1
• UniProt ID: O14926