FSCN2
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Official Full Name
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) -
Overview
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
FSCN2;fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus);fascin (Strongylocentrotus purpuratus) homolog 2 (actin bundling protein, retinal);fascin-2;RFSN;RP30;Fascin homolog 2, actin bundling protein, retinal Strongylocentrotus purpuratus;Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein, retinal;FSCN2_HUMAN;Retinal fascin
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FSCN2-1278H | Recombinant Human FSCN2 protein, His-tagged | E.coli | Human | His | Gln8~His258 |
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| Fscn2-1279M | Recombinant Mouse Fscn2 protein, His-tagged | E.coli | Mouse | His | Gln8~Asn278 |
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| FSCN2-4091C | Recombinant Chicken FSCN2 | Mammalian Cell | Chicken | His |
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| FSCN2-6055M | Recombinant Mouse FSCN2 Protein | Mammalian Cell | Mouse | His |
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| FSCN2-852H | Recombinant Human FSCN2 | Mammalian Cell | Human | His |
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| FSCN2-2682H | Recombinant Human FSCN2 Protein (Gln8-His258), His tagged | E.coli | Human | His | Gln8-His258 |
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| FSCN2-2977H | Recombinant Human FSCN2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| FSCN2-2977H-B | Recombinant Human FSCN2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| FSCN2-3371M | Recombinant Mouse FSCN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FSCN2-3371M-B | Recombinant Mouse FSCN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FSCN2-4512H | Recombinant Human FSCN2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FSCN2-5078HF | Recombinant Full Length Human FSCN2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 492 amino acids |
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Involved Pathway
FSCN2 involved in several pathways and played different roles in them. We selected most pathways FSCN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FSCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FSCN2 has several biochemical functions, for example, actin binding,actin filament binding,protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by FSCN2 itself. We selected most functions FSCN2 had, and list some proteins which have the same functions with FSCN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin filament binding | FSCN1,FSCN2B,ADD2,PPP1R9A,LIMA1,FMNL1,ANTXR1,CORO2B,TLN1,SYNE2 |
| protein binding, bridging | ADAP2,TRIM6,COL1A2,FSCN1,AMFR,FGB,ANXA1,LOR,TRIM22,COL8A2 |
| actin binding | LSP1,FLII,MACF1,ALKBH4,MYHZ1.2,EPS8L1,VASPA,DIAP3,MYO19,KIF18A |
Interacting Protein
FSCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FSCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FSCN2.
Resources
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References
- Soundararajan, R; Won, J; et al. Gene Profiling of Postnatal Mfrp(rd6) Mutant Eyes Reveals Differential Accumulation of Prss56, Visual Cycle and Phototransduction mRNAs. PLOS ONE 9:-(2014).
- Ohmen, J; Kang, EY; et al. Genome-Wide Association Study for Age-Related Hearing Loss (AHL) in the Mouse: A Meta-Analysis. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY 15:335-352(2014).
