Recombinant Human FRS2 protein, MYC/DDK-tagged

• Cat.No.: FRS2-23H
• Product Overview: Recombinant Human FRS2, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: FRS2 played an important role in many functions.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 56.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FRS2 fibroblast growth factor receptor substrate 2 [ Homo sapiens ]
• Official Symbol: FRS2
• Synonyms: FRS2; fibroblast growth factor receptor substrate 2; FRS2A; FRS2alpha; SNT 1; SNT1; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1; SNT; SNT-1
• Gene ID: 10818
• mRNA Refseq: NM_006654
• Protein Refseq: NP_006645
• MIM: 607743
• UniProt ID: Q8WU20
• Chromosome Location: 12q15
• Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; Frs2-mediated activation, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem
• Function: fibroblast growth factor receptor binding; insulin receptor binding; neurotrophin TRKA receptor binding; phosphatase activator activity; protein binding; transmembrane receptor protein tyrosine kinase adaptor activity