Recombinant Human FREQ, GST-tagged

• Cat.No.: FREQ-13001H
• Product Overview: Recombinant Human FREQ protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-190
• Description: This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: NCS1 neuronal calcium sensor 1 [ Homo sapiens ]
• Official Symbol: NCS1
• Synonyms: NCS1; neuronal calcium sensor 1; FREQ, frequenin (Drosophila) homolog , frequenin homolog (Drosophila); NCS 1; frequenin homolog; frequenin-like protein; frequenin-like ubiquitous protein; FLUP; FREQ; DKFZp761L1223
• Gene ID: 23413
• mRNA Refseq: NM_001128826
• Protein Refseq: NP_001122298
• MIM: 603315
• UniProt ID: P62166
• Chromosome Location: 9q34.11
• Function: calcium ion binding; protein binding