Recombinant Human FRAT1 Protein, GST-tagged

• Cat.No.: FRAT1-4490H
• Product Overview: Human FRAT1 partial ORF (NP_005470.2, 181 a.a. - 279 a.a.) recombinant protein with GST tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Protein Length: 181-279 a.a.
• Description: The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq
• Molecular Mass: 36.63 kDa
• AA Sequence: RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FRAT1 frequently rearranged in advanced T-cell lymphomas [ Homo sapiens ]
• Official Symbol: FRAT1
• Synonyms: FRAT1; frequently rearranged in advanced T-cell lymphomas; proto-oncogene FRAT1; FRAT-1; frequently rearranged in advanced T-cell lymphomas 1; FLJ97193
• Gene ID: 10023
• mRNA Refseq: NM_005479
• Protein Refseq: NP_005470
• MIM: 602503
• UniProt ID: Q92837