Recombinant Human FOXP1 protein, DDK-tagged

• Cat.No.: FOXP1-16H
• Product Overview: Recombinant Human FOXP1 fused with DDK tag at C-terminal was expressed in Insect cells.

Specification

• Description: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: Insect cells
• Species: Human
• Tag: Flag
• Form: 50mM Tris-HCl pH8.0, 100mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles.
• Molecular Mass: 75 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FOXP1 forkhead box P1 [ Homo sapiens ]
• Official Symbol: FOXP1
• Synonyms: FOXP1; forkhead box P1; forkhead box protein P1; 12CC4; fork head related protein like B; glutamine rich factor 1; hFKH1B; HSPC215; PAX5/FOXP1 fusion protein; QRF1; glutamine-rich factor 1; fork head-related protein like B; FLJ23741; MGC12942; MGC88572; MGC99551
• Gene ID: 27086
• mRNA Refseq: NM_032682
• Protein Refseq: NP_116071
• MIM: 605515
• UniProt ID: Q9H334
• Chromosome Location: 3p14.1
• Function: DNA binding, bending; chromatin binding; double-stranded DNA binding; metal ion binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription factor binding; zinc ion binding