Recombinant Human FOSL1, GST-tagged

• Cat.No.: FOSL1-12965H
• Product Overview: Recombinant Human FOSL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-271a.a.
• Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FOSL1 FOS-like antigen 1 [ Homo sapiens ]
• Official Symbol: FOSL1
• Synonyms: FOSL1; FOS-like antigen 1; fos-related antigen 1; fra 1; FOS-like antigen-1; FRA; FRA1; fra-1
• Gene ID: 8061
• mRNA Refseq: NM_005438
• Protein Refseq: NP_005429
• MIM: 136515
• UniProt ID: P15407
• Chromosome Location: 11q13
• Pathway: Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Osteoclast differentiation, organism-specific biosystem
• Function: protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity