Recombinant Human FMOD Protein, MYC/DDK-tagged

• Cat.No.: FMOD-893H
• Product Overview: Recombinant protein of human fibromodulin (FMOD) was expressed in HEK293 with C-terminal MYC/DDK

Specification

• Description: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FMOD fibromodulin [ Homo sapiens ]
• Official Symbol: FMOD
• Synonyms: FMOD; fibromodulin; fibromodulin proteoglycan; SLRR2E; FM; KSPG fibromodulin; collagen-binding 59 kDa protein; keratan sulfate proteoglycan fibromodulin
• Gene ID: 2331
• mRNA Refseq: NM_002023
• Protein Refseq: NP_002014
• MIM: 600245
• UniProt ID: Q06828