Recombinant Human FLI1 Protein, GST-tagged

• Cat.No.: FLI1-4209H
• Product Overview: Human FLI1 full-length ORF ( AAH01670, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 75.46 kDa
• AA Sequence: MDGTIKEALSVVSDGQSLFDSAYGA AAHLPKADMAASGSPDYGQPHKINP LPPQQEWISQPVRVNVKREYDHMNG SRESPVDCSVSKCSKLVGGGESNPM NYNSYMDEKNGPPPPNMTTNERRVI VPADPTLWTQEHVRQWLEWAIKEYS LMEIDTSFFQNMDGKELCKMNKEDF LRATTLYNTEVLLSHLSYLRESSLL AYNTTSHTDQSSRLSVKEDPSYDSV RRGAWGNNMNSGLNKSPPLGGAQTI SKNTEQRPQPDPYQILGPTSSRLAN PGSGQIQLWQFLLELLSDSANASCI TWEGTNGEFKMTDPDEVARRWGERI SKPNMNYDKLSRALRYYYDKNIMTK VHGKRYAYKFDFHGIAQALQPHPTE SSMYKYPSDISYMPSYHAHQQKVNF VPPHPSSMPVTSSSFFGAASQYWTS PTGGIYPNPNVPRHPNTHVPSHLGS YY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FLI1 Friend leukemia virus integration 1 [ Homo sapiens ]
• Official Symbol: FLI1
• Synonyms: FLI1; Friend leukemia virus integration 1; Friend leukemia integration 1 transcription factor; EWSR2; SIC 1; proto-oncogene Fli-1; transcription factor ERGB; SIC-1
• Gene ID: 2313
• mRNA Refseq: NM_001167681
• Protein Refseq: NP_001161153
• MIM: 193067
• UniProt ID: Q01543